Blast from the past

Breakthrough in Wheat Blast Resistance: New Research from the John Innes Centre

The fight against wheat blast, a burgeoning threat to global food security, has made a significant leap forward thanks to groundbreaking research from the John Innes Centre. This new discovery could reshape our understanding of disease resistance in wheat and offers a promising avenue for combating one of the most devastating crop diseases.


The Significance of the Discovery

Wheat blast is a formidable disease that has rapidly spread since its first appearance in Brazil in 1985. Unlike many cereal diseases that have co-evolved with their hosts over millennia, wheat blast is relatively new, giving wheat plants little time to develop natural defenses. The disease’s rapid spread and devastating impact make it a critical target for agricultural research aimed at ensuring global food security.

The new research identifies a gene that confers resistance to wheat blast, marking a major milestone. This gene, discovered using advanced gene discovery methods at the John Innes Centre, offers a new tool for breeding wheat varieties that can withstand this aggressive pathogen.


An Unexpected Source of Resistance

One of the most surprising aspects of this discovery is the source of the resistance gene. Traditionally, scientists search for disease resistance genes in wheat varieties from regions where the disease is prevalent. However, the John Innes Centre team found that wheat varieties with resistance to powdery mildew—a disease common in the colder, wetter climates of the northern hemisphere—also offer protection against wheat blast, a disease of humid subtropical regions.

The resistance gene, identified on chromosome 2A of the wheat genome, is known as Pm4. This gene has been selected for powdery mildew resistance in European wheat breeding programs for years. Now, it appears that this gene can also provide protection against wheat blast, suggesting that plant breeders may need to look beyond tropical varieties to find effective resistance traits.

“These findings were completely unexpected,” said Professor Paul Nicholson, a leader of the research group at the John Innes Centre. “They suggest that if you want to find resistance to wheat blast, you should also look at varieties that come from non-tropical regions where they already have resistance to mildew.”


Implications for Global Food Security

The discovery of the Pm4 gene’s dual resistance capabilities has far-reaching implications for global food security. As wheat blast continues to spread, particularly in countries like Bangladesh and Zambia, the need for resistant wheat varieties becomes increasingly urgent. The research team’s identification of this gene opens up new possibilities for breeding wheat varieties that can withstand both powdery mildew and wheat blast.

Dr. Tom O’Hara, the lead author of the study, emphasized the immediate benefits for breeders. “This is the first cloned blast resistance gene—unlike previous blast resistances, we have been able to pinpoint the exact gene. This means that our findings could be of great immediate benefit to breeders.”

The team will continue to use gene discovery methods to search among European wheat varieties for additional blast resistance genes. This ongoing work aims to expand the genetic toolkit available to breeders, providing stronger and more durable resistance to wheat blast.


Conclusion

The discovery of the Pm4 gene’s resistance to wheat blast represents a significant breakthrough in the fight against this emerging threat to global food security. By revealing an unexpected source of resistance, the research underscores the importance of exploring diverse genetic backgrounds for disease resistance traits. As the world faces increasing challenges from climate change and evolving pathogens, such innovative approaches are essential for safeguarding our food supply.

For more details on this groundbreaking research, visit the John Innes Centre website and stay tuned for further updates on advancements in agricultural science.


This discovery not only provides hope for combating wheat blast but also highlights the potential of cross-disciplinary research in uncovering new solutions to global agricultural challenges.

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